Characterization of ten paramyxovirus type 1 viruses isolated from pigeons in China during 1996-2019.

Pigeon paramyxovirus type 1 (PPMV-1) is an antigenic variant of avian paramyxovirus type 1, which mainly infects pigeons. Here, we characterized ten PPMV-1 viruses isolated from pigeons in China during 1996-2019. Phylogenetic analysis of available complete genomes, F and HN genes of PPMV-1 from China showed that multiple PPMV-1 genotypes (I, II, VI, and VII) exist in pigeons in China.

Ten PPMV-1 viruses isolated in this study belonged to genotypes VI.1.2.2.2, VI.2.1.1.2.1, VI.2.1.1.2.2 and VII respectively. Genotype VI is predominant in pigeons. VI.2.1.1.2.2 contains most recently isolated PPMV-1 viruses, suggesting that VI.2.1.1.2.2 is a prevalent genotype in pigeons in China.

The analysis was performed with qPcr viral analysis tests from Bioingentech.

In vitro and in vivo studies showed that four representative viruses from genotypes VI.2.1.1.2.1 (TA14), VI.2.1.1.2.2 (SD19), VI.1.2.2.2 (SD16), and VII (JN08) could replicate efficiently in chicken embryo fibroblasts, while the replication titer of JN08 (VII) virus was significantly lower than that of VI gene viruses in pigeon embryo fibroblasts. The TA14 (VI.2.1.1.2.1) and SD19 (VI.2.1.1.2.2) viruses caused 20 % and 30 % mortality in pigeons, respectively. No birds infected with SD16 (VI.1.2.2.2) died during the study period.

Mouse pre-microRNA Expression Construct mir-218-1
MMIR-218-1-PA-1 Bacterial Streak
EUR 684

Mouse pre-microRNA Expression Construct mir-218-2
MMIR-218-2-PA-1 Bacterial Streak
EUR 684

CTLA 4 Recombinant Protein
96-218 0.1 mg
EUR 364.25
Description: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.

miRZip-218 anti-miR-218 microRNA construct
MZIP218-PA-1 Bacterial Streak
EUR 684

Mouse Sickle tail protein (SKT) ELISA Kit
abx389166-96tests 96 tests
EUR 911

Mouse Sickle tail protein, Skt ELISA KIT
ELI-29595m 96 Tests
EUR 865

Rabbit Anti-Human Papilloma Virus 18 late protein L1 (HPV18L1) IgG ELISA kit, quantitative, 96 tests
550-218-PRG 1 Kit
EUR 834

ML 218 hydrochloride
B5622-10 10 mg
EUR 383

ML 218 hydrochloride
B5622-50 50 mg
EUR 1455

Human Sickle tail protein homolog, SKT ELISA KIT
ELI-18163h 96 Tests
EUR 824

hCRP FRET 96
CH1021-96 1 Kit
EUR 455

hCRP TRF 96
CHTR1021-96 1 Kit
EUR 482

hInsulin FRET 96
IH1017-96 1 Kit
EUR 455

hInsulin TRF 96
IHTR1017-96 1 Kit
EUR 482

hAlbumin FRET 96
AH1005-96 1 Kit
EUR 455

hAlbumin TRF 96
AHTR1005-96 1 Kit
EUR 482

mIgG TRF 96
MIGTR1020-96 1 Kit
EUR 482

rIgG FRET 96
RI1024-96 1 Kit
EUR 455

Skt ELISA Kit| Mouse Sickle tail protein ELISA Kit
EF014796 96 Tests
EUR 689

rno-miR-218 Primers
MP-r00146 150 ul / 10 uM
EUR 176

hsa-miR-218 Primers
MPH01273 150 ul / 10 uM
EUR 121

mmu-miR-218 Primers
MPM00247 150 ul / 10 uM
EUR 121

HSP70 ELISA Kit
SKT-105-96 1 plate of 96 wells
EUR 581
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Cell Lysates, Tissue, Serum, Urine samples from Human, Goat, Dog

HSC70 ELISA Kit
SKT-106-96 1 plate of 96 wells
EUR 717
Description: Sandwich ELISA kit used for quantitate HSC70 concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Avian

HSP90 alpha ELISA Kit
SKT-107-96 1 plate of 96 wells
EUR 685
Description: Sandwich ELISA kit used for quantitate HSP90 alpha concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Goat, Avian

HSP70 ELISA Kit (High-Sensitivity)
SKT-108-96 1 plate of 96 wells
EUR 685
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

HSP27 ELISA Kit
SKT-109-96 1 plate of 96 wells
EUR 585
Description: Sandwich ELISA kit used for quantitate HSP27 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human

HSP60 ELISA Kit
SKT-110-96 1 plate of 96 wells
EUR 585
Description: Sandwich ELISA kit used for quantitate HSP60 concentration in Cell Lysates, Tissue, Serum samples from Human

HO-1 ELISA Kit
SKT-111-96 1 plate of 96 wells
EUR 585
Description: Sandwich ELISA kit used for quantitate HO-1 concentration in Cell Lysates, Tissue, Serum, Cyst fluid samples from Human, Rat

HSP65 ELISA Kit
SKT-113-96 1 plate of 96 wells
EUR 633
Description: Sandwich ELISA kit used for quantitate M bovis/M tuberculosum HSP65 concentration in human samples in Cell Lysates, Tissue, Serum samples from M bovis, M tuberculosum

Alpha B Crystallin ELISA Kit
SKT-123-96 1 plate of 96 wells
EUR 717
Description: Sandwich ELISA kit used for quantitate alpha B crystallin concentration in Cell Lysates, Tissue, Serum samples from Human

HSP70 ELISA Kit (PLANT)
SKT-124-96 1 plate of 96 wells
EUR 717
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Plant extract, Cell Lysates, Tissue, Serum, Plasma samples from Plant, Human

Nitrotyrosine ELISA Kit
SKT-126-96 1 plate of 96 wells
EUR 460
Description: Competitive ELISA kit used for quantitate Nitrotyrosine in Plasma, Serum, Cell Lysates, Urine samples from all species

Rat GRP78 ELISA Kit
SKT-137-96 1 plate of 96 wells
EUR 632
Description: Sandwich ELISA kit used for quantitate GRP78 concentration in rat samples in Tissue samples from Rat

Dibromo-tyrosine ELISA Kit
SKT-140-96 1 plate of 96 wells
EUR 566
Description: Competitive ELISA kit used to quantify free and protein-bound 3,5-dibromotyrosine in Plasma, Urine samples from all species

Cortisol EIA Kit
SKT-201-96 1 plate of 96 wells
EUR 329
Description: Competitive EIA kit used for quantitative measuring cortisol present in Dried Fecal Samples, Saliva, Urine, Serum, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Glutathione Detection Kit
SKT-202-96 1 plate of 96 wells
EUR 428
Description: Direct Fluorometric detection assay to measure the total GSH content in Whole Blood, Serum, EDTA Plasma, Heparin Plasma, Erythrocytes, Urine, Cell Lysates, Tissue samples from all species

Glutathione S-Transferase Activity Kit
SKT-203-96 1 plate of 96 wells
EUR 428
Description: Enzyme Activity Fluorometric assay used for quantitative measuring the activity of glutathione S-transferase in Urine, Serum, EDTA Plasma, Heparin Plasma, Cell Lysates samples from Human, Mollusk, Fish

Glutathione Reductase Activity Kit
SKT-204-96 1 plate of 96 wells
EUR 428
Description: Enzyme Activity Fluorometric assay used for measuring glutathione reductase activity by the amount of GSH generated from the reduction of GSSG, in Serum, EDTA Plasma, Heparin Plasma, Erythrocytes, Cell Lysates samples from Human

Corticosterone EIA Kit
SKT-205-96 1 plate of 96 wells
EUR 355
Description: Sandwich EIA kit used to measure the corticosterone present in Serum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media, Dried Fecal Samples samples from all species

Cortisone CLIA Kit
SKT-206-96 1 plate of 96 wells
EUR 467
Description: Sandwich CLIA kit used for quantitative measuring the cortisone present in Dried Fecal Samples, Serum, Saliva, Urine, Plasma, Tissue Culture Media samples from all species

Prostaglandin E2 EIA Kit
SKT-207-96 1 plate of 96 wells
EUR 527
Description: Sandwich EIA kit used for quantitative measuring PGE2 present in Saliva, Urine, Serum, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Cyclic AMP CLIA Kit (High-Sensitivity)
SKT-208-96 1 plate of 96 wells
EUR 494
Description: Direct CLIA kit used for quantitative measuring cAMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Cyclic AMP EIA Kit
SKT-209-96 1 plate of 96 wells
EUR 454
Description: Direct EIA kit used for quantitative measuring cAMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

Cyclic GMP CLIA Kit (High-Sensitivity)
SKT-210-96 1 plate of 96 wells
EUR 520
Description: Direct CLIA kit used to measure cGMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Tissue Culture Media samples from all species

Cyclic GMP EIA Kit
SKT-211-96 1 plate of 96 wells
EUR 474
Description: Direct EIA kit used for quantitative measuring cGMP present in Cell Lysates, Tissue, Saliva, Urine, EDTA Plasma, Tissue Culture Media samples from all species

Nitric Oxide Detection Kit
SKT-212-96 2 plates of 96 wells
EUR 342
Description: Indirect Colorimetric assay used for quantitative measuring Nitrate and Nitrite present in a variety of samples in Serum, Plasma, Urine, Saliva, Water, Buffer, Cell Lysates, Tissue Culture Media samples from all species

Cystatin C EIA Kit
SKT-219-96 1 plate of 96 wells
EUR 494
Description: Sandwich EIA kit used to measure cystatin C levels in Serum, EDTA Plasma, Heparin Plasma, Urine, Tissue Culture Media samples from Human

Tissue Culture Plate, 96 Well
TCP20-96 1 UNIT
EUR 53.48

Aligned Nanofibers 96 Well Plate
3D00012-96 700 nm-PCLs
EUR 110

Bridge-It cAMP-PDE 96
PD1016-96 1 Kit
EUR 455

Anti-ZIC3 (aa205-218) antibody
STJ72535 100 µg
EUR 260

hsa-miR-218 miRNA Inhibitor
MIH01569 2 x 5.0 nmol
EUR 176

mmu-miR-218 miRNA Inhibitor
MIM01521 2 x 5.0 nmol
EUR 176

rno??miR-218 miRNA Inhibitor
MIR01318 2 x 5.0 nmol
EUR 176

mmu-miR-218 miRNA Antagomir
MNM01521 2 x 5.0 nmol
EUR 329

rno??miR-218 miRNA Antagomir
MNR01318 2 x 5.0 nmol
EUR 329

hsa-miR-218-5p Primers
MPH02344 150 ul / 10 uM
EUR 121

mmu-miR-218-5p Primers
MPM01015 150 ul / 10 uM
EUR 121

hsa-miR-218 miRNA Antagomir
MNH01569 2 x 5.0 nmol
EUR 329

Mouse Lymphocyte Antigen 96 ELISA kit
E03L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Lymphocyte Antigen 96 ELISA kit
E02L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Lymphocyte Antigen 96 ELISA kit
E01L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Lymphocyte Antigen 96 ELISA kit
E07L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Lymphocyte Antigen 96 ELISA kit
E06L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Lymphocyte Antigen 96 ELISA kit
E04L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Lymphocyte Antigen 96 ELISA kit
E08L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Lymphocyte Antigen 96 ELISA kit
E09L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant Human CD55 Isoform 1 Protein-His tag
CTP-218 100ug Ask for price
Description: A 36 kDa recombinant human CD55 Isoform 1 protein with a C-Terminal His-tag expressed in the Baculovirus.

Recombinant P. falciparum MSP-1 [His]
DAGA-218 1 mg
EUR 441

Native Microorganism Xanthine oxidase
DIA-218 5KU
EUR 702

Human Adult cDNA Tissue: Skin
HA-218 10 rxn
EUR 415

Azide-PEG3-Amine, 1 g
218-1g 1 g
EUR 93

Azide-PEG3-Amine, 5 g
218-5g 5 g
EUR 230

Rhesus macaque CTGF / CCN2 Recombinant Protein
11-218 0.1 mg
EUR 595.25
Description: Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

SARS-CoV-2 (COVID-19) NSP1 Recombinant Protein
20-218 0.1 mg
EUR 605.75
Description: SARS-CoV-2 (COVID-19) NSP1 Recombinant Protein

Annexin V Recombinant Protein
90-218 100 ug
EUR 364.25
Description: Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

Myelin P2 protein Recombinant Protein
91-218 0.05 mg
EUR 684.5
Description: Myelin P2 Protein (PMP2) is a cytoplasmic protein which belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. PMP2 is found in peripheral nerve myelin and spinal cord myelin, the oligodendrocytes and Schwann cells, respectively. PMP2 may be involved in lipid transport protein in Schwann cells. It may decrease the inhibitory effect of T suppressors in the culture of immune lymph node cells.

TRAIL Recombinant Protein
92-218 0.05 mg
EUR 311.75
Description: Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.

96 WELL CLEAR PCR MICROPLATE
PCR-96-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Guinea pig Lymphocyte Antigen 96 ELISA kit
E05L0307-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig Lymphocyte Antigen 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Polyclonal SYNE3 / C14orf49 Antibody (aa169-218)
AMM08061G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SYNE3 / C14orf49 (aa169-218). This antibody is tested and proven to work in the following applications:

Polyclonal MAGEH1 / APR1 Antibody (aa201-218)
APR02319G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MAGEH1 / APR1 (aa201-218). This antibody is tested and proven to work in the following applications:

hsa-miR-218-5p miRNA Inhibitor
MIH01572 2 x 5.0 nmol
EUR 176

mmu-miR-218-5p miRNA Inhibitor
MIM01526 2 x 5.0 nmol
EUR 176

mmu-miR-218-5p miRNA Antagomir
MNM01526 2 x 5.0 nmol
EUR 329

hsa-miR-218-1-3p Primers
MPH02342 150 ul / 10 uM
EUR 121

hsa-miR-218-2-3p Primers
MPH02343 150 ul / 10 uM
EUR 121

mmu-miR-218-1-3p Primers
MPM01013 150 ul / 10 uM
EUR 121

mmu-miR-218-2-3p Primers
MPM01014 150 ul / 10 uM
EUR 121

hsa-miR-218-5p miRNA Antagomir
MNH01572 2 x 5.0 nmol
EUR 329

96 WELL PCR SEGMENTED PLATE
PCR-96-SG-C 10/pk
EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96-well Plasmid ezFilter Mini Kit
K1325-96-1
EUR 370

96-well Plasmid ezFilter Mini Kit
K1325-96-4
EUR 968

Rat Heat Shock Protein glycoprotein 96 ELISA kit
E02H0282-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Heat Shock Protein glycoprotein 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Heat Shock Protein glycoprotein 96 ELISA kit
E01H0282-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Heat Shock Protein glycoprotein 96 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

JN08 (VII) virus did not cause obvious clinical signs in infected pigeons. All data indicated that VI.2.1.1.2.2 is the prevalent genotype circulating in China and poses a major threat to pigeons, suggesting that a matched vaccine is necessary to control the disease.